Cannabis, Psychedelics and Brain Health

Episode 3 of Just Say KNOW with Maria Calabrese dives into the science and stigma surrounding psychedelics and cannabis with special guest Dr. Manesh Girn, a leading psychedelic neuroscientist. Together, they explore how substances like psilocybin and cannabis are transforming the future of mental health by enhancing neuroplasticity—the brain’s natural ability to adapt and heal.

In this episode, you’ll learn:

• • How psilocybin therapy works and why it’s showing promise in clinical research
  • The differences between cannabis compounds like THC, CBD, and CBG—and what they actually do

• How these natural medicines may support emotional resilience, mental wellness, and personal growth

Dr. Girn also shares groundbreaking research from his work at UCSF and opens up about his own life-changing experiences with psilocybin that inspired his path in neuroscience. Whether you're curious, cautious, or completely new to this space, this episode will help you see these substances through a new, evidence-based lens.

Tune in, get informed, and Just Say KNOW.